There's no such thing as a will of nature. That's either a piece of superstition or another term for your own moral preferences.
So why does the term "unnatural" exist then?
Well, for a couple reasons. One is to demarcate between things that are possible and impossible given the natural laws that obtain in our universe. But there's also a use of that term that reduces to a moral judgment, as when people declare that, e.g., homosexuality is unnatural.
Is that also a term for moral preferences?
As I pointed out above, sometimes it is used in that way.
Let's take gravity for instance. On earth things fall down, not up. That's the will of nature right there.
No, that's not the will of nature. Only agents can will things. That's just natural law. As far as I can tell, this term 'will' is introduced in order to subtly ascribe some kind of spooky authority to nature, as though you
ought not contradict nature's will. But, of course, if 'nature's will' is interpreted in a non-normative sense, then it makes no sense to rebuke somebody for contradicting nature's will, since they wouldn't be able to contradict it in the first place.
You'd do well to point out how these people have gone against the "will" of nature. If by this term you just mean 'natural law' then presumably they
can't go against the will of nature.
But of course if you believe that everything has a right to fall up you're going to disagree with me.
If you mean to suggest that I hold a view like that, then you apparently don't know how folks like me use the term 'right.' A right entails enforceable obligations on the part of moral agents, not inanimate things or nature. So of course I don't think people have a right to fall upwards. If they somehow manage to do so, however, then good for them.