What bothered me was the "simulacra" that these animals have become, much like the American Buffalo, and numerous other macrofauna, notably birds of New Zealand that are restricted to a few small islands set aside for conservation. These animals are, unfortunately, genetically limited populations acting as a museum. In a state of nature life radiates genetically causing speciation, resulting in what we now call biodiversity (only because it is dying, the same function as multiculturalism in an acultural society), but these animals lack that organic emergence. I suppose this could contrast with Raccoons and English Sparrows, among a great many other species, that subsist with great efficiency in human dominated environments, but without the intention of the human subject.
So for me, it wasn't so much about inbreeding as much as the flaws inherent in conservation.
Inbreeding and genetic recession is a part of nature. Some species of fungi lose their ability to reproduce sexually altogether. The same thing can happen in higher chordates: http://www.nature.com/nature/journal/v444/n7122/abs/4441021a.html
What are the flaws? Frame them in ways we could fundamentally change them. Those seem like the best courses of action in lieu of something better like human re/depopulation. For me, there is an innate drive to preserve biodiversity at all costs, even if it means setting aside small relict populations. Maybe it isn't so much as innate as ingrained by watching countless nature documentaries as a child where conservation was constantly drilled into my head. Well it worked. When it comes to the survival of other species, that is when I am most interventionist. Fuck sending seal team 6 after Islamic boogymen created by the post-Canaanite-religion construct, go after poachers, illegal loggers, and people who work for companies or governments who continue to cause irreversible environmental harm, especially extinctions. The endangered Rhino>the diseased village that depends on illegal sale of the horn to sustain. Poaching endangered animals should be a Capital crime world wide. Eye for an eye is dated, except in the case of tigers poached for tiger penis soup.
Since there is no divine magic from my frame of mind, in lieu of supernatural, higher value has to be gleaned from the natural processes. Nature's beauty can only be appreciated wholly by her diversity. Bio diversity has to be respected above the temporary lives and comfort of humans. There are billions of us. If we do not as a species alter our mindset towards the Earth and the other species we are crowding off of it daily, it will prove that man is evolutions greatest failure. I do not fault the animal for not being able to survive off our scraps or migrate on our roads like rats and racoons.
Other than our friends Metallica, the idea of a God that Failed is something theologians(I use the term liberally to apply it to 'Tallica, admittedly) typically can side step, but as an naturalist, I would much rather not have to believe humanity's and ergo my own existence is evolution's gravest error. If I am fundamentally honest, I believe we probably have already been convicted based on the evidence as is, but never the less I would like to take some effort to try and minimize nature's mistake by correcting and reversing our own.