Bill Bailey has me in stitches. Bill Hicks, Dylan Moran, Ricky Gervais, Mitch Hedberg, Ross Noble, Jim Gaffigan, Patton Oswalt, David Cross—mainly for the Pitchfork burning he dished out on their own site—Lenny Bruce, Zach Galifianikis, Louis C.K. and Demetri Martin all also have their merits. Most of those are recent comedians... I'm biased to guys I've seen live. I think my favorites are Hicks, Bailey and Martin at the moment.
Also, recently, Knocked Up broke my funnybone.